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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '6182c1a2ec05fee209ea5a556afd47e28332461b346729ffcc9a5a042e6e0ad1' 
  AND token = 'uQP9Nl4yIawOYAsR9M3LuJf258VjJrxh1aSEWmzY0Xo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}