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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a3282e39307f62e0897d1a812980df2aa2770f639a4edfe823e82ca666240b95' 
  AND token = 'v+wSodhlSzsXiMR3dEwHiC3JtnsWzAY2/0QUKJSLxz8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}