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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '6c880f0b492b26dfd897485cfefa5a0eaad5c979b087c4055f4e705f097a5e6f' 
  AND token = 'RJJsSSq9g6nyNs3YvbO/9iKB/ryufX8IOFaSMleCdNw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}