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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'da7484ab65b68bc5d82f567785608121867abe192e8a9ebddba742c52c09fe2f' 
  AND token = 'Tlmvl53eC2uXJhqpRnELQdTH6UWeCPOBLcFjID7bfDM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}