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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'cce042dc8cf06e8c119bd8c05b632d6c2edc63d88c5d7c56147337a79db18d3b' 
  AND token = 'vpR7gESWWwvhtuAqkXLLxXfFkTP7vz1m6nhC3HQmKLo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}