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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1080e9146ebb4df055ee4321506688b2aae4b4ec87d335136c63f8ec063f2bce' 
  AND token = 'NhufbvTynbFpSAuSFC2/fyUpgXXo8cy1JCmOsomWiVY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}