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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8b37c4807fe505bddcf141bc9b8fbb178b4c970e7e524795b34378e572c84270' 
  AND token = 'Wwtt1x9YApNhYEtVtz/o+KUKlQQ2c+VlIHkNnxI3H4A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}