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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3fd3459c1ad50ae1cb3998d7f261a7b199b2041df4f871c0c21626a6da02edb5' 
  AND token = 'KnIFiWZCmTwxf73ckGu9XtiZ9N+yzJ3W2aRcqyiei0k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}