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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a5fe93585d674292076fa8fe7378892b7e92decd7e86412deaabf79189b503df' 
  AND token = 'B4mW/3eEwzPq2nQOewX6v4nvYt5fIDhkEDRa5SQ66Ak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}