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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '45529b468dfbd9dad2392563e80fe045fd3f602856d9814d833c5d6a1c1eebb9' 
  AND token = 'G6dVbRUSRAga9oW+0DNbzepxM6d4vxFuPTK+L08pMNM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}