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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8284048943e9b11af584598dc093b6981ed2d58b822b29d1d1ffbf1a8d93d4e9' 
  AND token = 'mCGnKj6OXpayRjiLWKtaAFg0x8zYeB9tzpWCmlSTlZo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}