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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '059d1b8fd3c15853e2cd575bd216aa404d264ec306f945a5ed0f0cee46c30183' 
  AND token = 'cOFIT9aNuOKanMS2JLZs8IJ0DdEPqEtmm7JjN+omjNs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}