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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a5161ac50ae67ba1df8307dd03da4491e70957b6f844d235916b26f9110d9bdf' 
  AND token = 'Ud+9uqec/OV+YW4MJ/6csmzM1E9ZWY5SKXr/uQUfEuA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}