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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'cfbb98f83cd5b48e13a91bf9073f051e28e7c4bc8189e977bb03c5591d05c795' 
  AND token = 'UXWiXhqq+FO9l+n/kKyYq9/+QiKQCwyapnnUEkEzhgg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}