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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a5a07d4b0f4cc191d545d824eac077bef1297c4428a326d2410936994bb8ff80' 
  AND token = '2HA9V1WHdDzH2ixr0uR+tdamqkcRYeg2YcuDAkXMEUc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}