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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'cde9110d1f4de1677147a679543cf7282e7d02f5e27be99c5fe51ec9e024f920' 
  AND token = 'tmXli0ONUNPegiz81Vjj8H06QfksEgRqOzPfiXJH/Kc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}