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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd2ed8c627cf192de8b779529d09d6bdb2a2d7dce264ba8162473601e8cde389f' 
  AND token = 'WMozG2fOpgTDcNCZsXsHsVcwRBZ45CkvHF4W4XOvC6E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}