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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4e0e233ea0403334aa4c9aad13087254e0e050825e21a667bfeece3b1ba2a778' 
  AND token = 'esv5aN3QQVERGkuZJ+p792Db4b+Q8mk1YgZG1MJ9ZMU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}