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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4f7f5aee2d02bc8bd1c041b1b16261761622c2c3d8b6770476a4f98495d219f1' 
  AND token = '24DA3RGpiUhAynPUtRkckAZ0jGEcMUS0sj00Sfc9CaE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}