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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '7578c1a67b5c14b3f408722e227bc22b67dda890a859f0c3d517a0900a151d1d' 
  AND token = 'o8OQA1DuPioQZ+zk8DrGRKCYBbLfO7ttKTf9WogKUHY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}