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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ac1b1bc67ee74ee802b79edbf8cb4dd0ca5662a4465d5a88cf397dc46344b169' 
  AND token = 'esgZH3nv61SwOVUFXdx32PP+d46fb+nU6i2RBiB/b/c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}