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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f78af58adfaabc3008aa0a0f906195c46699de003f3b4a0e27a5c9bb14be8f13' 
  AND token = 'ME3lCVeuHKeOPxH8FALL9koURHmuM36Onx8jXIsJVwg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}