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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '6289853291ef3f743e9a83a01e5f2c07450d0c2e5c9612e0d8febff8bcea5f22' 
  AND token = 'rtIEL9+xIQQVZZQceqwsrs8Q1kG9JzmOw7IzSfGUPfc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}