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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4cf308a8e978766bf6fcfaee823c618a05ad26167843d92a804d02f07a368cce' 
  AND token = 'Ve5P5PXMUkqLldj3WwVXh1PoeZCm/lWFhoE62JhmYf4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}