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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'df40f4fe5db6f8cd05a9fb66692dff52f0841fd88d5452cc6e7c850504412ab6' 
  AND token = 'Vya38bTKV1ogjVaCCSZ61052ux6q+d21Lfc3i6fWhgc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}