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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '22e1ed85c036ad8e9777b020a0ef65acd14e7a1574b8212dd6db2486fb254dab' 
  AND token = 's5+LMqRy1mSdQFgK6RyWTrDPNis58T0UFiR8ODP4q0w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}