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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '09b428b7f9ae2c064c4047f31dd8e87ffde18c531219c95844e37b0878bb0217' 
  AND token = 'QseXvJcMXBkk52J6RPVidQko3h9j4/XE2IuEQfD4bEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}