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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5e18b9e28070dffd232bcb21a7fc33c65503ad3a125b721ee0afc3b28419a50e' 
  AND token = 'H8RijUd2YCoBk3Q2RLTjXu1aZYaQn1B7N32ZZp3SbVc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}