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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '441fe7247ef071d6995298e71c84446f5d5b8a6bf334e0d6ec9c2218ec80b446' 
  AND token = 'fwBvLs3ilq7aI4HFp58j85JFbjqnirpeYNGPs7yBYL4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}