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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '7450b8d8bab6c4ae0e078202b21bedc4c823246b95b5c962d1792302538b300c' 
  AND token = 'N3lssaexwo6K2th6fIJJQQbO66h67zKi7GUsfOhXz9g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}