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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4a722afe8aec664e566dd2f8c7bdf302e12ffb07ccc81089ac0f63273c4b65c3' 
  AND token = 'C1b2XkGIR8PnTj3Yp66dY0mUEZCqrJBZWij9DE4moak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}