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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2e28cc5affd8105d268d605df585b28be7b8fee4dac84292f577f6c7d93be6c8' 
  AND token = '2NsRoACvG1kqUMHP33unVVszNT3xE5nFVdcqyqTwlh8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}