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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8e854ac8b6c26bf25d7965f7abd64b89865f5c75aaf6ba99e50840ccf5ec7570' 
  AND token = '+LVOL72EIy5gbq1pR8wWg00P7nFoH+mTmOxs+7mCSrA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}