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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '9f27f17e83146f31c942fdc1cf44dd2f1e33485e2d5bd38a1e95a999e980a6f1' 
  AND token = 'XlDL2Hn8DK4Ip8lQ9FhtzDqNc6VyG7FlyJGj9O2cDEk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}