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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3e0c3af8a3e11239f6c9b91550acafca8131083d0a1e1640503f30d726b2d8e2' 
  AND token = '2nyIkdp4a6qtf+uWaAhdgC3nuICEay1hdd7nMFZ6nu8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}