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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4a1d265305fd5a3595af53ae6b44b55d3ebe10b31dfb3937fac989ad37faa106' 
  AND token = '43+8AhPypI6inEmZtLnEZfEabmvLGBzYR2PpHKRG3Tk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}