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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2e48fa31eef85e89ff5c709468b4b3effbfa1535bb4e76defbf30b5c6d991499' 
  AND token = 'EeUOaIH2D9faPj1VAPhPzkx/T6pXX4KS7L3h/hRtvSk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}