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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '428e6e536da55faa7f3b5b0406b4707e0871381dece8fe9d155796a6cdc106a3' 
  AND token = 'nhYIhrC71KIrZe1W+wQ1T7nkQki+OFfv4YUl4QB+jw4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}