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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '638d802cbf6f31deaaaa063b5a029745b24d9399c70244749cbac16c87486b51' 
  AND token = 'Pnut9TMbqZJkTeqPBabUJ9VTIS+JTXPlhBT/s5SAu8s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}