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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '537d666b35a6645c914dfeed5dac4257c7e4cacff5d321e1a40cd20dbad06c66' 
  AND token = 'Ae4NFmjUHR8GQVFqFA6ImsVQy+FuakyVc3iRDPap/Rs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}