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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '399635e42ce3c500a370fe4c8e8a9aad03450cc1df759c427b8a3027504586ad' 
  AND token = 'njy35e38G4ShfZAVqFFhGez7DAynq+n0Q7F3HZkowIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}