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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '39a7455711a3239dee17068447cc461d4e9dc05cb7d9e4c5b7e634229246fc59' 
  AND token = 'mJteaXz46pqUpPXyTASKpp3Ggz85E31wKHvvTWj26Is=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}