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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2b1b76a835c6dabc87c55f1b11d246f3c4e493fa9f8a3af53fd37d7f6f4a9586' 
  AND token = 'RWqvrtteI0EpFCXiuBlPkgSfFFDR4zj5GrxzAv9uAn4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}