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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '46c42894cbaf576b9e0a367d8c1813ad50c83d95bd6cac2632628fa03db7af16' 
  AND token = 'QLU73l9LUq0y61xpKXWBloIKEKbNLyRgwgbQuJ1xVgc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}