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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'aae11a2ceb81134fc4ba65e7025bb6dce573f308c939d828dbe29670190bd65f' 
  AND token = '6E/PAkoSLUCMBgCcG7S0zIq2TwDEtqTOx816qipm5L4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}