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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f43dc117bad2e8bd1c4cbcf5ad4b99c0bbae6733d0694e109139581a5c62187a' 
  AND token = 'pPhcigM13Tn5AHrGeKQGFQ94m5tORYP49Chjgy3cwA0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}