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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '12bb56fc15b745034fc4718e15db92a5e074563d761b56b1b0c6b1e9a6f35393' 
  AND token = 'ypmyM6zqsyqlDl3sixAVyRN9nuuzpn2Im3zeNNiLaXc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}