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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a7f351313b5c93e3a8622bfe83d880fba92242411a3761c0f5e9d21c9bce3271' 
  AND token = 'ESpXnp5Kf3a6Cqx16va+XrZesKXFYMhPbc5YPhg2tUE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}