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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd2fef21b0c2a976122128b82c02d8ecdc77a4b94b1421aa7e41e32a66324e411' 
  AND token = 'CKuaPR8njXW4NfG+egsz1kXDAPdfsFCTcQ/BuonHRUA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}