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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '510cb598ce4b4bd1ce05609da825e8fb5e3683e5e8a9f48c016065594a738394' 
  AND token = '+JrisFfU281Fm6l4ALWEI7thHk4OVsjGuLERZehyKZ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}